The eagerly-anticipated game will see two sides who've had a tricky start to the season battled it out for a much-needed three points, and Marcelo Bielsa's side will be confident of emerging victorious after winning both home and away in the league against Steve Bruce's side in the 2020/21 campaign.
Speaking ahead of the game, Bielsa was to expand on some recent self-criticism, and said: “I am never critical of my job or my labour without explaining why and I did it in the press conference beforehand. The job of a manager is not measured by the quality of the resources that he has but by those resources obtaining the result that we are looking for.
“Normally I don't have problem diagnosing the problems that we suffer but knowing what the problems are doesn't mean having a solution for them or solving them. You start using different resources and it is only good how you manage it if the reality changes.
“I clearly saw that the plan of the opponent (Liverpool) in the last game had a superior effect to the one I proposed for the game. We couldn't neutralise their set pieces, not because we ignored the strength of possibly the best two headers (of the ball) in the Premier League at the moment but because of the way we chose to combat it wasn't effective.”
Take a look at the latest news round-up from the Premier League, as the build-up to the weekend's action continues:
1. Barca could beat Chelsea to midfielder
Barcelona have been tipped to beat Chelsea to the signing of Dynamo Moscow youngster Arsen Zakharyan. The Catalan giants have been tipped to enter talks with his club in the coming weeks, after scouts were wowed by some of his recent displays. (Sport Witness) Photo: KIRILL KUDRYAVTSEV
2. Wilder wants Forest job
Ex-Sheffield United boss Chris Wilder is said to be keen on the vacant Nottingham Forest job. It had previously been claimed that Wilder would hold out to see if Steve Bruce would lose the Newcastle job, and look to fill the role if so. (Guardian) Photo: OLI SCARFF
3. Dyche signs new deal
Burnley boss Sean Dyche has signed a new deal with the club that will extend his stay to well over a decade, with the four-year deal keeping him there until 2025. He's been with the club since 2012, and got them promoted to the top tier back in 2014 and again in 2016. (Club website) Photo: LINDSEY PARNABY
4. Red Devils ready big wage increase for star man
Manchester United star Bruno Fernandes looks to be close to signing a new five-year deal with the club, that will see his wages rise to a hefty £250k per week. He scored 18 goals and provided 12 assists in the Premier League last season. (The Sun) Photo: Clive Brunskill
5. Duo jostle for Lacazette
La Liga duo Atletico Madrid and Sevilla have both been linked with a move for Arsenal striker Alexandre Lacazette. The Frenchman looks unlikely to sign a new deal, meaning the Gunners could opt to sell him in January so as not to lose him for nothing next summer. (Sport Witness) Photo: Marc Atkins
6. Guardiola frustrated over low attendance
Pep Guardiola has urged more Manchester City fans to attend their game against Southampton, after just over 38,000 fans attended their midweek Champions League game clash against RB Leipzig, despite their stadium having a 55,000 capacity. (BBC Sport) Photo: Richard Heathcote